Ecological Systems and Devices Annotation << Back CORRELATION ANALYSIS OF THE RELATIONSHIPS BETWEEN METABOLIC PROCESSES INDICES IN SMALL MAMMALS LIVING IN THE RADIOACTIVE CONTAMINATION AREA L.N. Rasina, A.N. Varaksin The study has been performed on small wood mice (Apodemus (S.) uralensis Pallas, 1811) inhabited two areas: 37 mice captured in the conventionally «clear» territory having 90Sr radioactive isotope content in soil less then 7 kBq/m2 and 45 mice in the East Ural radioactive trace (EURT) contamination zone with 90Sr soil content from 5 000 to 18000 kBq/m2. The matrix of the Pearson correlation coefficients (PCC) between thirteen biochemical parameters of lipid carbohydrate and protein metabolism were calculated, in total 78 PCC for each animal group. In animals of the control «clear» territory strong correlations were found between all biochemical indices. Most indices with strongest pair PCC grouped around the index named «MDA concentration in the liver», emphasizing the pivotal role of lipid metabolism and peroxidation in the energy supply of the cell-tissue functional activity. Many of these correlations are broken for the animals in the EURT area, indicating a change in the level of metabolic processes and key regulatory components of cells and cell-tissular functional activity under the radiation exposure. These changes are evidence of the functional adaptation to habitation in radioactivelycontaminated environment which is based on a higher level of peroxidation comparing to control animals. The obtained results can serve as a basis for development a database for physiological, population and species sustainability of metabolic homeostasis to industrial (primarily radiation) exposure. Keywords: area radioactive contamination; East-Ural radioactive trace (EURT); small wood mouse; chronic radiation exposure; small doses; correlation relationships between metabolic indices; correlation pleiads method. Contacts: E-mail: rasina@ipae.uran.ru Pp. 39-45.