Ecological Systems and Devices Annotation << Back CALS System for Environmental Monitoring of Arsenic Impurities in Colloidal Silicon Dioxide for Pharmaceuticals Bessarabov A.M., Trohin V.E., Gafitulina E.M., Tatarniceva E.V. A computer-aided quality management system (QMS) was developed for environmental monitoring of arsenic impurities in colloidal silicon dioxide used in the pharmaceutical industry. Since arsenic is one of the most toxic elements and can accumulate in the body, an information model was developed to systematize the monitoring of this critical indicator at the following hierarchical levels: manufacturers, product brands, quality indicators, analytical methods, and analytical equipment. The model is implemented within a QMS system based on CALS technologies, enabling the integration of disparate data into a unifi ed information space. The system contains information on modern domestic and foreign instruments capable of performing quantitative analysis in accordance with pharmacopoeial requirements. The proposed approach can be adapted for monitoring other critical impurities in pharmaceutical substances. Keywords: colloidal silicon dioxide, environmental monitoring, CALS system, arsenic impurity, atomic absorption spectrometry, X-ray fluorescence method, analytical instruments, pharmaceuticals. DOI: 10.25791/esip.9.2026.1615 Pp. 18-27.